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#470: Melatonin, Meal Timing & Glucose Tolerance

Sigma Nutrition Radio

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Type 2 Diabetes - Is There a First Phase Response?

The progression across glucose intolerance states to a diagnosis of type 2 diabetes is primarily characterized by a loss of that first phase insulin response. So if you don't have an adequate first phase response you can still be secreting insulin in the second phase but it's nowhere near sufficient to deal with the level of glucose there.

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