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Revised response criteria for high-risk MDS, machine learning guides diagnosis of bone marrow failure syndromes, and RhD-positive transfusions for Asian-type DEL patients with serologic RhD-negative typing

Blood Podcast

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The Role of Asian Type Dell in the Development of Childbearing Potential

The RHD-1-227A allele is found in greater than 95% of Dell individuals from east and southeast Asia. Since its molecular basis was first identified in 2001, the proper transfusion management of Asian Type Dell has been debated. A study from 2006 reported that Asian Type Dell recipients may not develop aloe anti-D after exposure to depositive red blood cells. The authors performed a clinical trial in which Asian Type Dell patients were transfused with depositive RBCs.

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