9min chapter

The Joe Rogan Experience cover image

#1670 - David Sinclair

The Joe Rogan Experience

CHAPTER

Controversy and Benefits of Metformin in Athletics

This chapter explores the controversy surrounding the use of metformin in athletics, shedding light on how data can be manipulated to exaggerate effects. The discussion covers the impact of metformin on muscle building, its potential to delay aging-related diseases, and the speaker's cautious approach towards its use, advocating for NAD boosters as a supplement. Additionally, insights into the mechanism of action of metformin in enhancing energy production and lifespan are provided, along with strategies to counteract its negative effects and optimize mitochondrial activity.

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