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Episode 11 - Acetaminophen and Metabolic Acidosis

The Curious Clinicians

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The Role of Acetaminophen in Metabolic Acidosis

Hadi: This is typically a more subacute toxicity. So for example, one patient had gotten 650 milligrams daily over the course of three weeks in a patient who was severely malnourished to cause a pretty significant five-oxaproline anti-agat metabolic acidosis. Hadi: It's something that we'll look for and it might sort of cause me to stop hunting for another cause of a metabolic acidosis but it doesn't necessarily help me change too much management other than maybe reduce the patient's standing tylenol dose or make it PRN.

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