The Limits of Maximum Human Life Expectancy

6min Snip

00:00

Play full episode

Summary

Transcript

Episode notes

With all of the exciting stuff that's happening, what do you think is the limit? Is there a ceiling? We're talking about getting more people to live to say 120 years. Or do you think that that may not be the ceiling and we could push up to 150, 200 years? And also, how long do you think it will take to kind of get to those numbers if they're possible? I think we're going to accidentally end up talking about longevity, escape velocity in this question actually. It's about increasing the amount of time we're able to do what we want with our lives.

Episode #262. Discover the science of getting older without getting old in this conversation with Dr Andrew Steele. From understanding what impacts your lifespan to revealing potential future scientific breakthroughs, this episode is an intriguing journey into the world of aging science.

Specifically, we discuss:

Intro (00:00)
Dr. Andrew Steele on aging (01:38)
Age-related diseases and lifespan extension (10:47)
Genetic factors, lifestyle, and gene editing for longevity (19:18)
Could gene editing help solve poor cholesterol? (27:52)
Rapamycin vs metformin for longevity (34:21)
The need for expert consensus on anti-aging interventions (39:47)
Insights on Bryan Johnson's Project Blueprint (47:50)
What are senolytic drugs? (51:24)
Yamanaka factors: is aging reversible at a cellular level? (1:05:18)
The rationale behind reversing aging and the future of interventions (1:17:42)
Lifestyle changes that slow the clock (1:25:40)
Calorie restriction and longevity (1:32:41)
Air quality, smoking, and vaping (1:44:54)
Stress, aging, and telomeres (1:51:18)
Are there biological reasons why women tend to live longer? (1:59:05)
Unpacking the buzz around HRT for men (2:04:14)
Environmental impact of extending human lifespan (2:07:23)
Outro (2:14:10)

Connect with Dr Andrew Steele on Twitter, Instagram, and Mastodon. Make sure to also head to his YouTube channel, where you’ll find videos on the ethics of prolonging lifespan and whether you can become biologically younger. Discover his book, “Ageless: The new science of getting older without getting old”, at https://andrewsteele.co.uk/ageless/, and read the free chapter on ethics here.

Enjoy, friends.

Simon

Want to support the show?

The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.

Simon Hill, MSc, BSc (Hons)

Creator of theproof.com and host of The Proof with Simon Hill

Author of The Proof is in the Plants

Watch the episodes on YouTube or listen on Apple/Spotify

Connect with me on Instagram, Twitter, and Facebook

Nourish your gut with my Plant-Based Ferments Guide

Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book