TWiV 1193: HPV or not to B
This Week in Virology
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Unraveling EBV's Immune Evasion Tactics
This chapter explores the interactions between the Epstein-Barr virus (EBV) and B-cell receptor complexes, highlighting the role of the viral proteins BALF and BARF in immune evasion. It discusses the implications of these findings for potential cancer therapies, particularly how the virus depletes antibody components through mechanisms like endocytosis and the ER-associated degradation pathway. The chapter concludes with insights into experimental methods used to study these processes, revealing the sophisticated strategies employed by EBV to manipulate the immune system.
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