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The Evolution of Epilepsy
The earliest written description of epilepsy comes from Mesopotamia around 2500 BCE in an ancient Sumerian text describing a focal, unaware tonic seizure. This condition was called antisubu and was thought to be related to the hand of sin, the God of the Moon. Some researchers have speculated that trepination, which is a practice that's been performed for thousands of years where you make a small hole in the skull and remove the bone, that was done to treat epilepsy. But it's something that we're never going to know for sure why people use trepination in ancient times.