Buddhism has long had a kind of diagnosis of the human condition and implied in that is a view of human nature there are certain claims about human nature made by Buddhism you know humans are prone to suffering happiness doesn't last gratification evaporates. Buddhist claim that humans don't always see the world clearly in fact we're prone to certain illusions and i think for starters both of those claims are borne out by the modern understanding of how natural selection shaped a human mind. If not seeing the world clearly and even having specific illusions about themselves of the world helped them get genes into the next generation then natural selection would favor suffering and illusion. It's an accurate description of what human evolution produced it