Challenges in Drug Development for Organ Transplantation

The chapter delves into the limitations and obstacles in drug development for organ transplantation, emphasizing the necessity of shifting focus towards long-term patient outcomes and developing innovative therapies. It discusses the need for new endpoints in clinical trials, regulatory adaptations to promote innovation, and the challenges in proving the superiority of new transplant drugs. The conversation also explores advancements in organ transplantation technologies and the importance of increasing organ availability while involving patient perspectives in regulatory evaluations.