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263. Cytokines Everywhere All at Once: Approach to CRS and ICANS

The Intern At Work: Internal Medicine

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Understanding CAR-T Therapy: Managing Cytokine Release Syndrome and Neurotoxicity

This chapter delves into chimeric antigen receptor T-cell therapy (CAR-T) and its role in cancer treatment, focusing on the mechanisms and management of cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS). It underscores the necessity for early diagnosis and treatment protocols, alongside recent advancements in the field.

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