Historical Evolution of Urticaria Understanding

Is it an allergy or an autoimmune vasculitis, or a little of both? Find out the story of urticarial vasculitis, how this disease was recognized and eventually sorted out from other types of urticaria.

·       Intro 0:12

·       In this episode 0:21

·       Case study 1:22

·       Chronic spontaneous urticaria, hives and nettles 7:57

·       Dermatographism and witchcraft? 10:15

·       Causes of urticaria 11:17

·       Theory of inflammation and histamines 11:40

·       Urticaria and treatments with histamines 12:09

·       Types of urticaria 13:02

·       Mayo Clinic study 13:39

·       Chronic urticaria as a manifestation of necrotizing venulitis 16:10

·       Connection between types of urticaria and leukocytoclastic vasculitis 20:02

·       More case studies 20:38

·       What do we know about treatments? 22:23

·       In conclusion 24:15

·       Coming up in part two 25:08

·       Thanks for listening 25:47

Disclosures: Brown reports no relevant financial disclosures.

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References:

Czarnetzki BM. Int J Dermatol. 1989;doi:10.1111/j.1365-4362.1989.tb01314.x.

Kolkhir P, et al. J Allergy Clin Immunol. 2019;doi:10.1016/j.jaci.2018.09.007.

McDuffie FC, et al. Mayo Clin Proc. 1973;48(5):340-8.

Natbony SF, et al. J Allergy Clin Immunol. 1983;doi:10.1016/0091-6749(83)90096-9.

Soter NA. N Engl J Med. 1977;doi:10.1056/NEJM197706232962505.