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TWiN 31: HIV-1 co-receptor shapes window for memory linking

This Week in Neuroscience

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Is CCR-5 a G Protein Coupler?

I'm thinking the signaling downstream of CCR-5 could end in changing gene transcription, or for example, insertion of different kinds of receptors at the surface. So they could be a catastrophe channel. And I'm also thinking NMDA receptors, there's like a NR3, or I don't know, this is 10 years ago, but the idea of metaplasticity. Just changing the composition of an NMDA receptor can then be, can regulate how plastic synaptic plasticity is in a given cell. Yeah, so I would say most likely, they didn't delve into that kind of mechanism of what C CR-5 is actually doing in this paper. But they do show that

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