Brain Ponderings podcast with Mark Mattson cover image

Bioelectronic Medicine, the Vagus, and the Inflammatory Reflex with Kevin Tracey

Brain Ponderings podcast with Mark Mattson

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Neuron Neuroscience - Vegas Nerve Stimulation Enhances Skilled Motor Learning

Vegas nerve stimulation drive selective circuit modulation through colonergic reinforcement but they found in mice that the biggest nerve stimulation enhances skilled motor learning. So it's, it enhances the ability of these mice to learn a certain moving their paw in a certain place essentially learning to move their paw ina certain place. And that's mediated by CEL Colleen signaling which I think you're also finding in the spleen right that there's a role for a CELColleen so that's kind of interesting this course they don't, they didn't really work out. They do think it's affecting what's going on actually in the motor cortex they did add some evidence for changes in theMotor cortex

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