How Does the Material Interact With the Immaterial?

We have consciousness, we have matter. We recognize mat real stuff and immaterial stuff. Immaterial stuff is not mystical as you might think. It's actually very ordinary stuff. In many ways, it's all the stuff that your entire practical, everyday life is composed of. But yet, scientifically, we haven't really been able to define it at all. Not even theoretically do we understand how the material could interact with the immaterial. These immaterial thoughts then shape my actions, which are material, physical actions. And vice versa? Seems like i could take some medication, or i can let drink some alcohol, get drunk, and that will affect my mood and my thoughts. How