Navigating Reimbursement Challenges with Network Meta-Analysis

This chapter explores the significance of network meta-analysis in demonstrating the value of new drugs during reimbursement negotiations, especially when direct comparisons are unavailable. It delves into the various scenarios where network meta-analyses are utilized post-marketing to showcase a drug's worth amid evolving markets and competition. The discussion also covers the challenges and nuances related to defining research questions, acquiring evidence, and addressing assumptions in network meta-analysis.