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The Incredibly Incredible Labrats
In the general population, it's hard to predict when some one might start developing dementia of any type. In marty's family, by contrast, there is a relatively predictable decade when their symptoms begin. And so researchers can test interventions and know with some confidence whether they are effective. If symptoms are lessened or don't appear in this predictable decade, then something is working. Like marty says, they're perfect labrats.