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#10 - Matt Kaeberlein, Ph.D.: rapamycin and dogs — man’s best friends? — living longer, healthier lives and turning back the clock on aging, and age-related diseases

The Peter Attia Drive

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Are You Swayed by the Data?

There are some data suggesting that the increase in a tofagy that one might see with rapaisin, which one would expect to see at least with m tork one inhibition, might be paradoxically not ideal in the active setting of cancer. So i think you have to be cautious in interpreting and increase in autofhagic markers in a disease as necessarily meaning that increased autohagy is causing or contributing to that. And it could be the case that, depending on how you activate autopagy, it could be a detrimental or it could be beneficial.

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