This episode is brought to you by InsideTracker, LMNT, and Joovv.

Today on The Dhru Purohit Podcast, Dhru sits down with Dr. Robert Lustig to talk about the impact of added sugar on mitochondrial health and metabolism and how to cut down on consumption on an individual and global scale.

Dr. Robert Lustig is a neuroendocrinologist with expertise in metabolism, obesity, and nutrition. He is also one of the leaders of the current “anti-sugar” movement that is changing the food industry, in part through his game-changing books. His latest work is Metabolical: The Lure and the Lies of Processed Food, Nutrition, and Modern Medicine.

In this episode, Dhru and Dr. Lustig dive into:

-What to expect after you significantly cut down on added sugar (3:04)

-The safest level of sugar to consume (8:12)

-The effects of large amounts of sugar inside the body (33:21)

-Sugar as the main driver of metabolic disease (40:06)

-How mitochondrial health impacts metabolic health (44:30)

-Eight drivers of disease and how to fight them (50:05)

-Omega-3 fats for cellular health (57:45)

-The role of omega-6 fats in creating health and disease (1:04:26)

-Gut health as a primary source of chronic inflammation (1:10:15)

-Should ultra-processed food be considered real food? (1:20:17)

-Dietary recommendations for safe sugar consumption (1:32:51)

-Recommendations for “safely” drinking alcohol (1:37:00)

-Why the makeup of our calories matters (1:44:03)

-Thin on the outside, fat on the inside (TOFI) (1:47:52)

-The three sites of fat deposition in the body (1:50:18)

-Findings from the SHINE study (1:56:36)

-The Metabolic Matrix (feed the gut, protect the liver, and support the brain) (2:07:45)

-Future directions for processed food and government policy (2:27:50)

-Action items for reducing the added sugar in your diet (2:43:29)

For more on Dr. Robert Lustig, follow him on YouTube @robertlustig, and his website, robertlustig.com.

Also mentioned in this episode:

-Get his book, Metabolical, here

-The SHINE randomized controlled trial

-Dr. Lustig’s new paper, The Metabolic Matrix

-Monch Monch: Dr. Lustig's fiber supplement

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Closing Bell: 5/7/25

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