Episode 118: AML Series, Pt. 4 - AML Induction: Approach to Initial Management
The Fellow on Call: The Heme/Onc Podcast
Understanding Mutations and the 'Seven Plus Three' Chemotherapy Regimen in AML
This chapter delves into the critical roles of tier one and tier two mutations in the management of acute myeloid leukemia (AML), emphasizing the importance of variant allele frequency for patient prognosis and treatment options. It also provides an overview of the 'seven plus three' chemotherapy regimen, tracing its historical origins back to a 1973 study by the Roswell Park Group.
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