
#934 iLet Bionic Pancreas with Ed Damiano
Juicebox Podcast: Type 1 Diabetes
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The Bi-Hormonal System and Insulin
We started by studying the bi-hormonal system and we chose a glucose target and aggressiveness factors. We found that with single hormone, we could safely have these targets up here and not have much hypoglycemia. And with thebi-h hormonal ones, we could have, safely have these Targets down here and still not have hypoglycemi because glucone is helping that. So it was about 15 MIG-PURDESTILATOR improvement by adding the second hormone and being able to use these lower targets. Withsingle hormone, as you lower the target, every time you lower the mean glucose but a concomitant increase in time below 54. With the
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