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Bioenergetics and Brain Health 2: Mitochondrial Dynamics, Biogenesis, Disposal, and Signaling

Brain Ponderings podcast with Mark Mattson

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Metabolic Switching and the Role of Ketones in Brain Energy

This chapter explores the metabolic shift from glucose to ketones during prolonged exercise or fasting, detailing how free fatty acids are converted into ketones in the liver. It also discusses the role of ketones, like beta-hydroxybutyrate, in enhancing gene expression and protein function, particularly the increase of BDNF levels in cells.

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