Thrombophilias During Pregnancy

A recent Cochrane review concluded that ventilation perfusion scan and CT angio were reasonable for the exclusion of BP in pregnancy. Now regarding treatment, adjusted dose anticoagulation is recommended for all women with acute VTE during pregnancy. International consensus guidelines suggest that after an initial treatment of 3-6 months dependent upon the type of VTE event, anticoagulated intensity can be decreased to intermediate or prophylactic dose at least 6 weeks postpartum. The management of newly diagnosed VTE consists of initiation of therapeutic subcutaneous low molecular weight heparin. Hospitalization may be indicated in cases of hemodynamic instability, a large clocked or maternal comorbidities.