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Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity
Huberman Lab
The Effects of Ketamine on Neuroplasticity
There's an additional and very important facet to this whole discussion about neuroplasticity in response to ketamine treatment for depression. If you recall the burst firing that induces that plasticity, I told you it induces plasticity, but I didn't tell you how. Now, you already could imagine some of the mechanisms. It could be insertion of those new glutamate receptors, those amper receptors that we talked about. However, even for that to happen, a bunch of other things have to happen first. But one of the key ones to understand is BDNF, which stands for brain-derived neutrophic factor.
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