Understanding Anaphylactic Transfusion Reactions

This chapter explores the definition and clinical presentation of anaphylactic transfusion reactions, especially in relation to IgA deficiency. It examines the rarity of true anaphylaxis during blood transfusions, contrasting it with other adverse reactions, while also analyzing the immunological mechanisms involved. The narrative traces the speaker's career from 1978, highlighting the evolution of understanding about IgA deficiency and its implications for diagnosis and patient care.