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TWiV 1213: Secrets of HepB cccDNA

This Week in Virology

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Impact of Antibiotics and Microbiome on Vaccine Response

This chapter explores the significant effects of antibiotics on immune responses, particularly in relation to the rabies vaccine. It discusses how antibiotic treatment can alter gut microbiome diversity, impacting B cell activation and antibody production. The analysis of various studies highlights the intricate relationships between immune cell types, gut bacteria, and vaccination efficacy, raising important questions about the role of the microbiome in immune modulation.

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