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Brad Marshall, Tucker Goodrich on Obesity Causes, Reductive Stress

David Gornoski

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Reductive Stress Is the Inverse of Oxidative Stress

Reductive stress is basically a, you know, it's kind of the inverse of oxidative stress. And that is essentially a buildup of too much energy in the mitochondria. All of our foods are made into acetyl CoA, glucose, fat, ethanol; all of them get burned to make NADH. So if you have too much acetyl Coa and you havetoo much NADH all in the mitochondrian, that's reductive stress in it. It's not producing the reactive oxygen species signal that it should be.

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