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Dosing of Diaretics in Heart Failure
High levels of billy ribon other circulating and ions, those will compete with lasigs and prevent it from getting secreted. And then if you have nephrotic ingumyou of the diretic itself is bound to albumen in the tuble, which vents it from actually finding its receptor as effectively. The thing i think people often forget ist the frequency of dosing to overcome the breaking effect,. But that these medicines really have to be dosed twice a day or more frequently to overcome the compensatory fluid reabsorption you get in the rest of the day.