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June 10, 2022 This Week in Cardiology Podcast

This Week in Cardiology

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How to Make Strong Conclusions in Substudies of Eskimia

Sub studies can help form questions for future trials, but you have to be cautious making strong conclusions. The main trial is statistically powered to reasonably avoid confusing signal from noise. When you start looking at fractions of that main study group, the risk of noise goes up. It's wrong to extrapolate findings of a five thousand patient trial to a sub set of only a few hundred or so patients.

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