
iwMyeloma Session II: the tumor microenvironment and mechanisms of resistance to targeted therapies
VJHemOnc Podcast
00:00
The Role of the Stroma in Inducing Resistance in Multiple Myeloma
This chapter explores how stromal cells in multiple myeloma produce cytokines and chemokines to attract other cells and enhance myeloma cell survival. It also discusses the impact of stromal cells on CAR T cells and the significance of IL-6 and STAT-3 signaling pathways in therapy response.
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