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iwMyeloma Session II: the tumor microenvironment and mechanisms of resistance to targeted therapies

VJHemOnc Podcast

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The Role of the Stroma in Inducing Resistance in Multiple Myeloma

This chapter explores how stromal cells in multiple myeloma produce cytokines and chemokines to attract other cells and enhance myeloma cell survival. It also discusses the impact of stromal cells on CAR T cells and the significance of IL-6 and STAT-3 signaling pathways in therapy response.

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