Matt is a clinical and research neurologist at Waikato Hospital, Hamilton, New Zealand. His foremost passion is to explore the potential feasibility, safety, and efficacy of metabolic strategies, particularly fasting and ketogenic diets, in creating alternate metabolic states that may benefit people with a variety of neurological disorders. His team conducted the world’s first randomized trials involving a ketogenic diet in people with Parkinson’s disease and Alzheimer’s disease, and is now applying fasting and ketogenic diet protocols in people with Huntington’s disease and amyotrophic lateral sclerosis. He is currently conducting a clinical trial in glioblastoma, which combines standard treatments with the most intensive fasting and ketogenic diet protocol ever applied to a group of patients with advanced cancer.
Twitter: @drmclphillips
Website: metabolicneurologist.com
Timestamps: 00:00 Trailer. 00:54 Introduction. 04:32 Clinical assessment includes muscle wasting, twitches, electromyography studies. 08:13 Limited confidence and patient enthusiasm key. Strong rationale. 10:40 Metabolic therapy seeks to improve overall health. 14:42 Fasting improves mitochondria efficiency, aiding weight loss. 17:42 Whole body disorder with inappropriate emotional control. 19:10 Participant noticed benefits of keto diet trial. 22:21 Case report highlights need for further exploration. 25:26 Low fat, high carb diet shows improvement. 28:48 Approach to migraine treatment using diet. 31:34 Continuous monitors and homogenized data in research. 34:51 Mitochondria's role in cancer and metabolic therapy. 36:46 Ketogenic diets reduce cancer cachexia in study. 39:54 Cancer cells consume glucose and amino acids. 44:07 Healthy exercise, rest, and sleep are important. 46:20 Glioblastoma trial and upcoming research in neurodegenerative diseases. 47:48 New Zealand good for small trials, but limited.
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