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Oct 21, 2022 This Week in Cardiology Podcast

This Week in Cardiology

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A Review of the Seminal Trials With Fineranone

The Figaro DKD trial had CV outcomes as its primary but the 13% reduction in the composite endpoint was driven by a 1.2% absolute risk reduction in heart failure hospitalizations. A European Heart Journal published a combined analysis of 6,500 patients in each group and that found modest reductions in both cardiac and renal composites. The big point from this meta-analysis was the mixture in baseline GFRs. Nearly all had greater than 25 GFR but also the urinary albumin to creatinine ratio.

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