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80| Cognitive Reserve – A Conversation With Dr. Yaakov Stern

Navigating Neuropsychology

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Cognitive Reserve and Alzheimer's Disease

Many people with high cognitive reserve and who also have advancing neuropathology are initially buffered against cognitive decline. But then, as you said earlier, they sort of fall off this cognitive cliff and decline rapidly. So we're thinking this picture might be somebody who's approaching that cliff. If I were that neuropsychologist, I would consider whether they might be in the early preclinical stages of AD. And I'd want to monitor them extra close because of the work on reserve.

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