Brain Ponderings podcast with Mark Mattson cover image

Bioelectronic Medicine, the Vagus, and the Inflammatory Reflex with Kevin Tracey

Brain Ponderings podcast with Mark Mattson

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What Causes Septic Shock and How Can It Be Treated?

Janice died of septic shock. She had no evidence of any infection even at post mortem. I decided then and there that I would try to figure out what what is it about septic shockWhat causes it how can it be treated. TNF stands for tumor necrosis factor, produced by macrophages. It's actually a pivotal molecule inside a kind storm. And the macrophages produce large amounts of TNF.

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