From Lex Fridman: https://lexfridman.com/demis-hassabis/
Transcripts from Karpathy's https://karpathy.ai/lexicap/0299-large.html
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00:37:13.160
So let's go to the basic building blocks of biology
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that I think is another angle at which you can start
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to understand the human mind, the human body,
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which is quite fascinating,
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which is from the basic building blocks,
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start to simulate, start to model
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how from those building blocks,
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you can construct bigger and bigger, more complex systems,
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maybe one day the entirety of the human biology.
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So here's another problem that thought
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to be impossible to solve, which is protein folding.
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And Alpha Fold or specifically Alpha Fold 2 did just that.
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It solved protein folding.
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I think it's one of the biggest breakthroughs,
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certainly in the history of structural biology,
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but in general in science,
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maybe from a high level, what is it and how does it work?
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And then we can ask some fascinating questions after.
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Sure.
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So maybe to explain it to people not familiar
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with protein folding is, you know,
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first of all, explain proteins, which is, you know,
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proteins are essential to all life.
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Every function in your body depends on proteins.
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Sometimes they're called the workhorses of biology.
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And if you look into them and I've, you know,
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obviously as part of Alpha Fold,
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I've been researching proteins and structural biology
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for the last few years, you know,
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they're amazing little bio nano machines proteins.
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They're incredible if you actually watch little videos
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of how they work, animations of how they work.
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And proteins are specified by their genetic sequence
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called the amino acid sequence.
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