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Ep. 95: “Lymphocyte Signaling” Featuring Dr. Gail Bishop

The Immunology Podcast

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Macrophages and Muscle: Unraveling New Roles

This chapter explores the unexpected interactions between macrophages and muscle spindles, revealing how these immune cells influence locomotion by interacting with mechanoreceptors. Through cutting-edge techniques like RNA sequencing and optogenetics, the study uncovers macrophages' ability to release glutamate, affecting muscle fiber activity. The discussion also transitions to novel approaches in T-cell engineering, emphasizing innovative strategies for targeted immune responses through synthetic suppressor T-cells.

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