How to Measure Oxygen Exposure in a Non Evasive Way

Most of the literature hyper oxia in adults and so far in ptiatrics has been measurements of ptwo, usually one time measurement. We were really interested in two things: figure out how to measure oxygen exposure in a non evasive way,. And the second one, how to quantify that exposure in a more robust and continuous way. The idea was if we know that certain oxygen levels are adequate for normal function, then you don't need more than that. So our goal was to come up with a way to non evasively measure the amount of oxygen in excess that patients were being exposed to.