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Chapter Five: Functions of the Distal Nephron

Channel Your Enthusiasm

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A New Mutation Causes Hypertension

Gordon cyndrum or pseudo hypo aldostronism two is characterized by hyper calemia, hyper tension and metabolic acidosis. It's exactly gittlman's turn on its head, the opposite of what Gordon sindram gets about half a sentence for. Wink cines for inhibits the sodium chloride co transporter to maintain a normal blood pressure in serum potassium. When the ubiquiating proteins are not present, wink for is free to inhibit the sodium ridco transporter in a less regulated manner. Depending on which of the four genes is mutated, the phenotype can vary from mild to severe blood pressure, potassium and acid abnormalities.

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