It's been hard to test directly whether heart rate can induce emotions like anxiety. Many of the methods to modulate a heart beats per minute can be non-specific and affects other parts of the body, making it difficult to pinpoint if heart rate itself is playing a direct role on emotional state. But this week Karl and his colleagues have shown a way to do just that in mice by using an optical pacemaker. This activation could happen from outside the body so no surgery or other invasive technique was required. It turned out it did but with a twist.

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