The Use of Relative Risk in Cholesterol-Loin Trials

The latest cholesterol-lowering agents are called PCSK9 inhibitors. They lower cholesterol more than statins, almost getting close to zero for the LDL in some cases. According to cardiovascular mortality, there were slightly more people died from cardiovascular disease in the treatment group. But you'd think if you're giving a drug that reduces the LDL to virtually John, you've proved the hypothesis that lowering it makes no bloody difference whatsoever.