49ers run game struggles and McCaffrey

Explosive offenses face vulnerable defenses as the Chicago Bears head to San Francisco for a high-stakes shootout against the 49ers. Can Brock Purdy maintain pinpoint accuracy against the league’s top takeaway unit, while Christian McCaffrey pushes through recent struggles on the ground? The discussion uncovers how both teams’ game plans hinge on turnover margins, time of possession, and the ability to capitalize on key matchups—especially with injuries impacting receiver depth and cornerback play.

Pass rush problems plague both squads, setting up a chess match of creative play calling and quarterback improvisation—Caleb Williams’ mobility and decision making come under the spotlight as threats to San Francisco’s struggling defensive line. Special teams could be the difference-maker, with Eddie Pineiro’s reliability and Skyy Moore’s electric returns. Will ball security and discipline tip the playoff implications in favor of the 49ers, or can the Bears capitalize on their opportunistic defense and emerging offensive talent?

San Francisco 49ers fans are treated to daily news and analysis with Locked On 49ers, hosted by football analyst Brian Peacock and former NFL/AFL cornerback Eric Crocker.

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