O'Zempic - Is There a Difference?

The potential for the max concentration can be like eight to 72 hours after taking the shot. O'Zempic, it was generally like, you know, after three or four days, that's kind of when you have your highest probability of the worst side effects. Whereas with Mungero, I had to go back and look at this because I usually don't tell people to take Zofan until the day after.

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My guest this week is Caleb Greer, FNP-C.

This is one of the most anticipated episodes! Caleb (he’s a favorite in this community!) and I discuss the hot topic, GLP-1 agonists! Caleb breaks down what is a GLP-1 agonist, what are Semaglutides (Ozempic) and the new predecessor, GLP-1 agonist, Tirzepatide, a class of peptide that is being touted as the closest to a fat loss holy grail in a long time! Could Tirzepatide be a magical support for fat loss? Before you race to get it, there are very important pieces to learn on dosing and side effects/”black box warnings” because as we all know, there are no free passes in life…

Caleb compares these two drugs, discusses patient results, the promising benefits for high cholesterol, who is eligible, health challenges with PPIs and what to supplement, and foundations needed to be successful in any weight loss journey, because long-term health is never just, “a pill for every ill”!

Learn more about Caleb at www.daseinhealth.org

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Episode Takeways

[06:00] Let’s talk semaglutide (Ozempic)…

[11:35] Pancreatitis and thyroid cancer with Ozempic. What are the risks?..

[15:00] How do GLP-1 agonists help with addiction?

[18:30] Ozempic results and dosing…

[21:30] Importance of building good habits while on GLP-1 agonists..

[24:58] Do GLP-1 agonists impact digestion such as secretion of hydrochloric acid?

[34:20] Let’s talk Tirzepatide…

[37:55] How is Mounjaro different from Ozempic?

[44:50] Cholesterol and Mounjaro…

[50:40] What foundation work is needed before adding a GLP-1 agonist?..