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Itacitinib monotherapy for GVHD, the role of ERG in EVI1-driven AML, and germline DDX41 mutations in myeloid neoplasms

Blood Podcast

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The Role of EVI-1 in Leukemiaogenesis

EVI-1 expression is restricted to hematopoietic stem cells in normal hema. The EVI-1 locus can be rearranged by several types of chromosomal alterations. There is an unmet need for new and effective therapies, says the study.

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