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Episode 344: Neurology VMR – bilateral lower limb weakness

The Clinical Problem Solvers

CHAPTER

Differential Diagnosis of Bilateral Lower Limb Weakness

The chapter delves into analyzing a patient with bilateral lower limb weakness, considering possible causes from the brain, spine, nerves, or muscles. It discusses the differential diagnosis involving peripheral, spinal, and brain lesions, focusing on chronic conditions, infections, degenerative diseases, and genetic conditions like hereditary spastic paraplegia. The speakers highlight the importance of a detailed history, sensory involvement, systemic symptoms, and neurological examination in narrowing down potential diagnoses and localizing the issue.

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