This podcast episode features an in-depth conversation on metabolic therapies and their potential in cancer treatment, particularly focused on glioblastoma and other glycolytic cancers. Our guest, Dr Dom D'Agostino, a researcher and professor with a diverse background in neuroscience, molecular pharmacology, nutrition and physiology, has a particular interest in metabolic therapies. Dr Dom shares how manipulating the body’s metabolism through the glucose ketone index (GKI), therapeutic ketogenic diets, and redox therapies can improve cancer outcomes by reducing tumour growth and enhancing standard treatments like chemotherapy and radiation. We also explore the synergies of non-toxic therapies such as hyperbaric oxygen, metformin, and IV vitamin C, and how these could potentially reduce the side effects and overall outcomes of cancer treatment.

We cover:

🩺 Standard cancer care with and without metabolic interventions

💊 Managing seizures with ketogenic therapies - a superior alternative to anti-seizure drugs

🍽 The power of fasting and the importance of protein intake in chemotherapy and cancer augmentation

🔥 Why certain cancers are more susceptible to metabolic-based therapies

🔬 How overall mitochondrial health dictates cancer cell transformation

Dom also touches on the fundamental relationship between liver health and cancer growth and metabolic strategies to prevent cancer. If you're interested in the intersection of nutrition and cancer or wondering how far we are from keto becoming part of standard care, this is a must-listen episode.

Find Dom:

Website

Metabolic Health Summit

Metabolic Health Summit YouTube

Mentioned in this episode:

Cancer cases attributable to potentially modifiable risk factors

Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

Ketones inhibit mitochondrial production of reactive oxygen species

The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival

Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer

Metabolic management of glioblastoma ...with a restricted ketogenic diet

Clinical trials in progress