This chapter discusses a study comparing the effects of hydro-corrosone to placebo on survival without moderate or severe bronchopulmonary dysplasia (BPD) at 36 weeks post menstrual age and neurodevelopmental impairment at two years. While no statistically significant difference was found, the chapter highlights the small suggestion of a benefit for hydro-corrosone in terms of survival without BPD. It also explores secondary analyses based on baseline risk and severity of lung disease.
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What is the potential impact of delayed cord clamping on severe IVH and neurodevelopmental outcomes? We explore this and more in our latest episode. We kick things off with a deep dive into a riveting paper from the Archives of Disease in Childhood that scrutinizes the approaches to umbilical cord management and their effects on death and neurodevelopmental impairment.
We also discuss the heterogeneity of treatment effects of hydrocortisone by risk of bronchopulmonary dysplasia or death among extremely preterm infants in the National Institute of Child Health and Human Development Neonatal Research Network Trial with our EBNEO colleague Nic Bamat from CHOP.
Join us as we welcome Dr. Rene Shellhass, co-author of the recent paper on neonatal seizures, to discuss the six PICO questions from the paper and their implications for the neonatal community. We take a hard look at the use of EEGs in diagnosing and managing neonatal seizures and the challenges involved. To wrap things up, we highlight the long term outcomes of the OPTMIST-A trial —a must-listen for anyone involved in neonatal care. We guarantee you'll walk away from this episode with a lot of valuable insights, thank you all for listening.
As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.
Enjoy!