Challenges and Innovations in CAR T-Cell Therapies for Cancer

Exploring the complexities of developing personalized and off-the-shelf CAR T-cell therapies for cancer treatment, this chapter discusses the challenges of scaling individualized treatments and the need for more accessible, standardized options. From using donor T cells to genome editing for safe treatments to modifying cells for immune evasion, the speakers highlight ongoing human trials and the advancements in CRISPR technology for improved therapy outcomes.