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Ep. 40: “Bacterial Pathogens” Featuring Drs. Kristin Patrick and Robert Watson

The Immunology Podcast

CHAPTER

Gasdermin D and Cell Death Dynamics

This chapter explores the critical role of gasdermin D in various cell death pathways, particularly pyroptosis and necroptosis, with an emphasis on its function during tuberculosis infections. It highlights the complex interplay between mitochondrial homeostasis, reactive oxygen species, and inflammatory processes that influence disease progression. Furthermore, the discussion touches on the broader implications of these findings in understanding immune responses to different pathogens.

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