Navigating Transfusion Challenges in Sickle Cell Disease

This chapter examines the unique complications of blood transfusions in sickle cell disease patients, focusing on the risks of delayed hemolytic reactions and hyperhemolysis. It underscores the essential need for careful transfusion management and the importance of serological matching to mitigate risks, especially in patients with a history of alloimmunization. The discussion highlights the urgency for improved patient records and the potential for advancements in risk assessment to ensure better patient outcomes.