Navigating the Complexities of Gabapentin Research

This chapter explores the intricacies of observational research in medication selection, focusing on gabapentin and its implications for patient safety, particularly regarding fall risks in older adults. It emphasizes the use of an active comparator design to minimize bias and provide realistic insights, while also discussing the limitations of retrospective studies. The authors highlight the need for careful consideration of individual patient profiles and the potential risks associated with gabapentin's varying dosages.