HER2 Mutation in Non-Small Cell Lung Cancer

The epidemiology is different by disease. In breast cancer, where 20% are HER2 amplified, which then produces the expression,. The genetic aberration is amplification. And that's just increased gene copy number in breast and gastric. Even in GI cancer, where again, TDXD and HER2 positivity is a big issue, colon, upper GI, I think it's mainly over expression there also.